This vaccine helps prevent:
—which causes a sore throat with thick covering in the back of the throat
—which causes painful muscle tightening all over the body; also known as lockjaw
—which causes bad coughing spells that make it difficult for infants to eat, drink, and breathe; also known as whooping cough
The Tdap vaccine contains diphtheria and tetanus toxoids, and acellular (small, purified pieces) pertussis germ.
is given to children ≥ 7 years old, adolescents, and adults to protect against tetanus, diphtheria, and
The vaccine is given as an injection, usually into the arm or thigh.
Tdap is routinely recommended for children aged 11 years or older, regardless of whether or not they completed the DTaP series. Tdap can also be given to:
- Children aged 7-10 years who have not been fully vaccinated
- Children (aged 11 years and older) and adults who did not get the Tdap should receive the vaccine followed by a tetanus and diphtheria (Td) booster every 10 years
- Adults who
have never received Tdap
- Pregnant women (or adolescents) after
weeks gestation, for each pregnancy, even if they have received Tdap in the past
If you or your child has not been fully vaccinated against
tetanus, diphtheria, and pertussis, talk to the doctor.
Most people tolerate the vaccines without any trouble. The most common side effects are:
- Pain, redness, or swelling at the injection site
- Mild fever
- Abdominal pain
Uncommon symptoms include:
- Fever over 102ºF
- Severe gastrointestinal problems
- Severe headache
is sometimes given to reduce pain and fever that may occur after getting a vaccine. In infants, the medication
may weaken the vaccine's effectiveness. However, in children at risk for seizures, a fever lowering
may be important to take. Discuss the risks and benefits of taking acetaminophen with your doctor.
Most people should receive their vaccinations on schedule. However, individuals in whom the risks of vaccination outweigh the benefits include people who:
- Have had a life-threatening allergic reaction to Tdap
- Have had a severe allergy to any component of the vaccine to be given
Have gone into a
within seven days after a dose of Tdap
Talk with your doctor before getting the vaccine if you have:
- Epilepsy or other nervous system problems
- Severe swelling or severe pain after a previous dose of any component of the vaccination to be given
- Guillain-Barre syndrome
- Moderate or severe illness
—wait until you recover to get the vaccine
The best way to prevent diphtheria is to get vaccinated.
Promptly clean all wounds and follow-up with your doctor for medical care to prevent a tetanus infection.
You can help prevent pertussis by keeping infants and other people at high risk away from infected people.
In the event of a
outbreak, all people who may have been exposed should be brought up to date with the vaccination. It is important to protect infants by isolating those who have the infection. Diagnosing the disease as quickly as possible can help control future outbreaks.
WHERE CAN I GET MORE INFORMATION?
Centers for Disease Control and Prevention. FDA approval of expanded age
indication for a tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine.
MMWR Morb Mortal Wkly Rep.
Vaccinations for adults. Immunization Action Coalition website. Available at:
http://www.immunize.org/catg.d/p4030.pdf. Updated August 2014. Accessed August 27, 2014.
Fisman DN, Tang P, Hauck T, Richardson S, Drews SJ, Low DE, Jamieson F.
Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling.
BMC Public Health.
Friedrich MJ. Research aims to boost pertussis control.
Pertussis (whooping cough) vaccination. Centers for Disease Control and Prevention, National Immunization Program website. Available at:
http://www.cdc.gov/vaccines/vpd-vac/pertussis/default.htm. Updated July 29, 2014. Accessed August 27, 2014.
Tdap vaccine: what you need to know. Centers for Disease Control and Prevention website. Available at:
http://www.cdc.gov/vaccines/hcp/vis/vis-statements/tdap.pdf. Updated May 9, 2013. Accessed August 27, 2014.
10/30/2009 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed: Prymula R, Siegrist C, Chlibek R, et al. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials.
11/4/2011 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed: Centers for Disease Control and Prevention (CDC). Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant aged <12 months—Advisory Committee on Immunization Practices (ACIP), 2011.
MMWR Morb Mortal Wkly Rep.
4/1/2014 DynaMed's Systematic Literature Surveillance
http://www.ebscohost.com/dynamed: Bridges CB, Coyne-Beasley T, et al. Advisory Committee on Immunization Practices recommended immunization schedule for adults aged 19 years or older—United States, 2014.
MMWR Morb Mortal Wkly Rep. 2014. 63(7):110-112.
Last reviewed June 2014 by Fabienne Daguilh, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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