Anything that causes irritation, inflammation, fluid retention, or an abnormal growth in or around the carpal tunnel can cause carpal tunnel syndrome, including:

  • Repetitive movements of the hands, wrists, or fingers—especially overactive use of a computer keyboard, certain musical instruments, or hand tools
  • Use of vibrating equipment or tools
  • A narrow carpal tunnel (due to heredity or other causes)
  • Wrist injury:
    • Burns
    • Broken bones
    • Compression or crush injuries
  • Arthritis leading to swelling within the carpal tunnel
  • Diabetes
  • Raynaud's disease, which impairs blood flow in the hands
  • Water retention due to:
  • Hormone-related conditions, such as:
  • Medications, such as:
    • Birth control pills
    • Cortisone pills or shots
    • Some high blood pressure drugs
  • Tumors and cysts in the carpal tunnel