THURSDAY, Nov. 29 (HealthDay News) -- Boys whose testes have not
descended at birth have an increased risk of developing testicular
cancer later in life, a new study says.
The findings raise the question of whether these boys should be
regularly monitored to lower their potential risk for testicular
cancer, the researchers said.
When testes fail to descend into the scrotum and remain in the
abdomen, the condition is called cryptorchidism. It's the most
common birth defect in boys and affects about 6 percent of newborn
Researchers analyzed 12 studies published between 1980 and 2010
that examined the link between cryptorchidism and testicular
cancer. Based on the collective findings of those studies, the
researchers calculated that boys with cryptorchidism were nearly
three times more likely to develop testicular cancer later in life
than those without cryptorchidism.
The findings are published online Nov. 28 in the
Archives of Disease in Childhood.
It's not known how certain aspects of cryptorchidism and surgery
to correct the disorder may affect the risk of developing
testicular cancer, said Robert Carachi, of the department of
surgical pediatrics at the Royal Hospital for Sick Children in
Glasgow, Scotland, and colleagues.
The most important question raised by the study is whether the
increased risk of testicular cancer is significant enough to
require regular follow-up for males born with cryptorchidism, the
researchers said in a journal news release.
Testicular cancer is the most common cancer in men aged 20 to
45. Worldwide rates of the cancer have increased substantially over
the past few decades.
The Nemours Foundation has more about