Brand Name(s):
  • AK-Sulf¶
  • Bleph-10®
  • Bleph-30®
  • Cetamide®
  • Sodium Sulamyd®
  • Blephamide®(as a combination product containing Prednisolone, Sulfacetamide)
  • FML-S®(as a combination product containing Fluorometholone, Sulfacetamide)¶
  • Vasocidin®(as a combination product containing Prednisolone, Sulfacetamide)
WHY is this medicine prescribed?

Ophthalmic sulfacetamide stops the growth of bacteria that cause certain eye infections. It is used to treat eye infections and to prevent them after injuries.

HOW should this medicine be used?

Ophthalmic sulfacetamide comes as a solution (liquid) to instill in the eyes, and an ointment to apply to the eyes. The eye drops usually are instilled every 2 to 3 hours during the day and less frequently at night; the ointment usually is applied four times a day and at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use sulfacetamide exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

To instill the eye drops, follow these steps:

  • Wash your hands thoroughly with soap and water.
  • Check the dropper tip to make sure that it is not chipped or cracked.
  • Avoid touching the dropper tip against your eye or anything else; eye drops and droppers must be kept clean.
  • While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.
  • Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.
  • Brace the remaining fingers of that hand against your face.
  • While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
  • Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.
  • Place a finger on the tear duct and apply gentle pressure.
  • Wipe any excess liquid from your face with a tissue.
  • If you are to use more than one drop in the same eye, wait at least 5 minutes before instilling the next drop.
  • Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.
  • Wash your hands to remove any medication.

To apply the eye ointment, follow these instructions:

  • Wash your hands thoroughly with soap and water.
  • Avoid touching the tip of the tube against your eye or anything else; the tube tip must be kept clean.
  • Holding the tube between your thumb and forefinger, place it as near to your eyelid as possible without touching it.
  • Brace the remaining fingers of that hand against your face.
  • Tilt your head backward slightly.
  • With your index finger, pull the lower eyelid down to form a pocket.
  • Squeeze a 1/4- to 1/2-inch (0.6- to 1.25-centimeter) ribbon of ointment into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
  • Blink your eye slowly; then gently close your eye for 1 to 2 minutes.
  • With a tissue, wipe any excess ointment from the eyelids and lashes. With another clean tissue, wipe the tip of the tube clean.
  • Replace and tighten the cap right away.
  • Wash your hands to remove any medication.
Are there OTHER USES for this medicine?

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What SPECIAL PRECAUTIONS should I follow?

Before using sulfacetamide eye drops or eye ointment,

  • tell your doctor and pharmacist if you are allergic to sulfacetamide, sulfa drugs, sulfites, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other eye medications and vitamins.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using sulfacetamide, call your doctor immediately.
  • you should know that your vision may be blurred during your treatment with sulfacetamide eye ointment. Avoid rubbing your eyes even if your vision is blurred. Do not drive a car or operate machinery if you are unable to see clearly.
  • tell your doctor if you wear soft contact lenses. If the brand of sulfacetamide you are using contains benzalkonium chloride, wait at least 15 minutes after using the medicine to put in soft contact lenses.
What should I do IF I FORGET to take a dose?

Instill or apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill or apply a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Sulfacetamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • temporary stinging or burning of the eye
  • increased redness, itching, or swelling of the eye that continues for more than 48 hours
What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not let it freeze and do not use discolored eye drops (yellowish brown to deep reddish brown). Throw away any unused part of your prescription. Do not save it to use for another infection. Talk to your pharmacist about the proper disposal of your medication.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

If you still have symptoms of infection after you finish the sulfacetamide, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

¶This branded product is no longer on the market. Generic alternatives may be available.

AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: April 15, 2011.