Calcium channel–blockers are used to treat hypertension, angina, heart arrhythmias, and other heart-related conditions.

Examples of drugs in this family include:

  • Amlodipine (Norvasc)
  • Bepridil hydrochloride (Vascor)
  • Diltiazem (Cardizem, Cardizem CD, Cardizem SR, Dilacor XR, Tiamate, Tiazac)
  • Felodipine (Plendil)
  • Isradipine (DynaCirc, DynaCirc CR)
  • Nicardipine hydrochloride (Cardene, Cardene SR)
  • Nifedipine (Procardia, Procardia XL, Adalat, Adalat CC)
  • Nimodipine (Nimotop)
  • Nisoldipine (Sular)
  • Verapamil (Calan, Calan SR, Covera-HS, Isoptin, Isoptin SR, Verelan)

Possible Decreased Action of Drug

Taking calcium and vitamin D supplements might interfere with some of the effects of calcium channel-blockers.1-7

Ginkgo Biloba

Possible Decreased Action of Drug

According to a study in rats, ginkgo extract may cause the body to metabolize some calcium channel blockers more rapidly, thereby decreasing their effects.8

Naringen (a Citrus Bioflavonoid)

May Necessitate Reduction in Drug Dosage

Some evidence suggests that the bioflavonoid naringen may interact with medications in the calcium channel blocker family, increasing blood levels of the drug.9 This may necessitate a reduction in drug dosage.