Brand Name(s):
  • Plendil®
  • Lexxel®(as a combination product containing Enalapril, Felodipine)¶
WHY is this medicine prescribed?

Felodipine is used to treat high blood pressure. It relaxes your blood vessels so your heart does not have to pump as hard.

HOW should this medicine be used?

Felodipine comes as an extended release tablet to take by mouth. It is usually taken once a day. Do not crush, chew, or divide felodipine tablets. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take felodipine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Felodipine controls high blood pressure but does not cure it. Continue to take felodipine even if you feel well. Do not stop taking felodipine without talking to your doctor.

Are there OTHER USES for this medicine?

Felodipine is also used sometimes to treat Raynaud's syndrome and congestive heart failure. Talk to your doctor about the possible risks of using this drug for your condition.

What SPECIAL PRECAUTIONS should I follow?

Before taking felodipine,

  • tell your doctor and pharmacist if you are allergic to felodipine or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antiseizure medicines such as carbamazepine (Tegretol), phenytoin (Dilantin), and phenobarbital; cimetidine (Tagamet); erythromycin (E.E.S., E-Mycin, others); itraconazole (Sporanox); ketoconazole (Nizoral); ranitidine (Zantac); and vitamins.
  • tell your doctor if you have or have ever had heart, liver, or kidney disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking felodipine, call your doctor.
  • if you are having surgery, including dental surgery, tell your doctor or dentist that you take felodipine.
What SPECIAL DIETARY instructions should I follow?

Talk to your doctor about drinking grapefruit juice or eating grapefruit while taking felodipine.

Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Felodipine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • flushing (feeling of warmth)
  • dizziness or lightheadedness
  • weakness
  • fast heartbeat
  • heartburn
  • constipation
  • enlargement of gum tissue around teeth

If you experience any of the following symptoms, call your doctor immediately:

  • swelling of the face, eyes, lips, tongue, arms, or legs
  • difficulty breathing or swallowing
  • fainting
  • rash

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at Web Site] or by phone [1-800-332-1088].

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What should I do in case of OVERDOSE?

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to felodipine.

Good dental hygiene decreases the chance and severity of gum swelling. Brush your teeth regularly and schedule dental cleanings every 6 months.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

¶This branded product is no longer on the market. Generic alternatives may be available.

AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: October 1, 2010.